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Embryo Genetic Testing (PGT-M/PGT-A) provides insight into the genetic health of embryos before the critical embryo transfer stage. Our Preimplantation Genetic Testing (PGT) services offer two distinct approaches: PGT-M, for individuals with a family history of specific genetic disorders, and PGT-A, designed to comprehensively assess the chromosomal health of embryos.
PGT-M assists in avoiding embryos carrying particular genetic mutations, while PGT-A ensures the overall genetic integrity and chromosomal balance, making it an essential consideration for patients facing various fertility challenges such as advanced maternal age, recurrent miscarriages, or previous ART failures.
For patients interested in knowing the genetic viability of an embryo prior to embryo transfer, MCRM Fertility offers patients pre-implantation genetic testing (PGT). This testing determines whether an embryo is genetically “normal” by investigating the DNA within. This may be done through one of two processes:
PGT-M is rationally used for patients who have a family history of genetic abnormalities such as cystic fibrosis, fragile X syndrome, Tay-Sachs disease, Duchenne Muscular Dystrophy, etc. or inherited cancer syndrome. PGT-M allows for selection of embryos that do not contain the specific genetic mutation for which the test is completed. The draw back to this analysis is that it does not look at the entire set of chromosomes for the specific embryo.
PGT-A is genetic testing, similar to PGT-M, where DNA is extracted from the biopsied cells of an embryo and analyzed. Unlike PGT-M; however, PGT-A analyzes the entire set of chromosomes to ensure that the correct number is present. Along with the correct number of chromosomes, PGT-A also ensures there is the correct balance of chromosome sets; ensuring the patients the genetic integrity of the specific embryo.
When to Consider PGT-A
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17300 N. Outer Forty, Suite 205 Chesterfield, MO 63005
Phone: 636-778-9899
Fax: 636-778-9915
HOURS:
Mon-Fri, 8am-4pm
4809 E. 89th St South, Suite 100
Tulsa, OK 74137
Phone: 918-615-8484
Fax: 918-551-7421
HOURS:
Mon-Thu, 8am-4pm; Fri, 8am-12pm
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