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Ovarian PRP (Platelet-Rich Plasma) Therapy

What is ovarian PRP?

Ovarian PRP (Platelet-Rich Plasma) therapy is an emerging fertility treatment now available to patients of MCRM Fertility.  It involves injecting platelet-rich plasma (PRP), derived from your own blood, into the ovaries to potentially rejuvenate ovarian function. The goal is to enhance egg quality and/or increase the number of available eggs in individuals with diminished ovarian reserve or other fertility challenges.

Who Might Benefit from Ovarian PRP?

  • Ovarian PRP may be considered for:
  • Women with low ovarian reserve (low AMH, high FSH)
  • Women with poor response to ovarian stimulation
  • Women approaching or in early menopause
  • Women seeking natural conception or improved IVF outcomes

How Does Ovarian PRP Work?

Platelet-rich plasma contains growth factors that may stimulate ovarian tissue and support:

  • Follicle development
  • Improved egg quality
  • Enhanced hormonal activity (e.g., estrogen production)

Procedure Overview

Time required: About 1-2 hours (including PRP preparation, PRP administration and recovery)

  • PRP Preparation
    • A small sample of your blood is drawn
    • The blood is processed using a centrifuge to concentrate the platelets and growth factors.
  • PRP Administration
    • The PRP is injected into your ovaries under ultrasound guidance, usually via a transvaginal procedure.
    • Light sedation or local anesthesia may be used.
  • Recovery
    • Usually minimal; most patients return to normal activities within 24 hours.

Expected Outcomes

Some women who have utilized ovarian PRP have experienced:

  • Better IVF response
  • Improved hormone levels
  • Resumed menstrual cycles

It should be noted, not all patients experience benefits and success is not guaranteed. 

Frequently Asked Questions Regarding Ovarian PRP

Is ovarian PRP therapy painful?

The procedure is generally well-tolerated. Mild cramping may occur similar to ovulation pain.

How soon might one see results?

Some women notice changes within 2-3 months, especially, if they are undergoing fertility treatments like IVF.

Can I still do IVF or other treatment afterward? 

Yes. PRP is often used alongside or before IVF cycles to try to enhance the ovarian response.

Important Notes

  • Ovarian PRP is considered experimental
  • Ovarian PRP should be offered through a licensed fertility clinic with experience in the procedure
  • Always discuss realistic expectations and alternative options with your fertility specialist