Should Your Consider PGT-A with Your IVF Treatment?
By: Peter Ahlering, MD
All humans, at any age, have some risk of producing aneuploid embryos; that is, genetically abnormal embryos with more than or fewer than 46 chromosomes. We are able to detect whether an embryo is aneuploid or not through the use of pregenetic implantation testing for aneuploidy (PGT-A). Generally, aneuploid embryos are not transferred. A large study by Tiegs et al, that was uniquely designed gave support to this approach by not disclosing PGT-A results until after the outcome of the embryo transfer had occurred. The authors found that ZERO of the aneuploid embryo transfers led to babies born, and there were high numbers of miscarriages requiring d&c procedures that resulted. By contrast, nearly 70% of the euploid (favorable) PGT embryo transfers led to ongoing pregnancies.
At MCRM Fertility, we have observed similar results over the years. PGT-A has been highly beneficial for our patients. In the event of no euploid embryos, while emotionally difficult, it is important to know that it saves time, heartbreak and costs related to starting fresh with another egg retrieval and transfer.
Come talk to us about whether this important tool can help you with your fertility desires.