Could supplementation help slow the age-related fertility decline?
This is an interesting article, obviously it is done in aged mice, as opposed to humans. That said, many people utilize supplementation with antioxidant supplements such as Coenzyme Q10 (CoQ10), Resveratrol. There are many others that people feel may be beneficial to ovarian function, sperm function and/or egg and sperm “quality.” While no direct evidence indicates this, there is indirect evidence such as this article that suggests that such products might be beneficial. While the list of potential products that may be helpful is exhaustive (I have only mentioned a couple here) we can now add NMN (nicotinamide mononucleotide) to the list. This is readily obtained over-the-counter and the theory is that this medication, as well as, ones such as NR (nicotinamide ribonucleotide) may increase NAD levels. This is theorized to have a beneficial effect on mitochondrial function and cells.
Again, this is just an interesting article that may prove helpful to some people.
Peter Ahlering, M.D.